WHAT IS PLAMUMAB INJECTION?

Plamumab 40 mg Injection blocks the action of certain chemical messengers that are responsible for inflammation, swelling and redness associated with certain joint diseases.

USES OF PLAMUMAB INJECTION:

Adalimumab is used to reduce pain and swelling due to certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, ankylosing spondylitis). This medication is also used to treat certain skin disorders (such as plaque-type psoriasis, hidradenitis suppurativa). It works by blocking a protein (tumor necrosis factor or TNF) found in the body’s immune system that causes joint swelling and damage in arthritis as well as red scaly patches in psoriasis. Adalimumab belongs to a class of drugs known as TNF blockers. By reducing joint swelling, this medication helps to reduce further joint damage and preserve joint function.

POSSIBLE SIDE EFFECTS:

Adalimumab may rarely cause serious (possibly fatal) liver disease in people exposed to hepatitis B virus. Your doctor may order blood tests and watch for symptoms during treatment and for several months after your last treatment. Get medical help right away if you have any symptoms of liver damage, including: nausea/vomiting that doesn’t stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine.

COMMON SIDE EFFECTS MAY INCLUDE:

Tell your doctor right away if you have any serious side effects, including: fast/irregular/pounding heartbeat, new or worsening symptoms of heart failure (such as shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain), blood in the stools, mental/mood changes, severe headache, easy bruising or bleeding, leg painor swelling, numbness or tingling of the arms/hands/legs/feet, unsteadiness, unexplained muscle weakness, difficulty with speaking/chewing/swallowing/facial movements, visionchanges, joint pain, butterfly-shaped rash on the nose and cheeks.

DRUGS PRECAUTIONS:

Before using adalimumab, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as natural rubber/latex), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: current/recent/repeated infections (such as hepatitis B, TB infection, histoplasmosis), blood/bone marrow problems (such as low red/white blood cells and platelets), seizures, certain brain/nerve disorders (such as multiple sclerosis, Guillain-Barre syndrome), cancer, heart disease (especially heart failure), lupus.

Adalimumab can make you more likely to get infections or may worsen any current infections. Wash your hands well to prevent the spread of infection. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details.

DRUGS INTERACTIONS:

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Some products that may interact with this drug include: other TNF blockers (such as etanercept, infliximab), other drugs that weaken the immune system (such as abatacept, anakinra).

WHAT IS POLY MXB POLYMYXIN B 5,00,000 IU INJECTION ?

Poly MXB Injection belongs to the group of medicines known as antibiotics. It works by killing bacteria or preventing their growth. Polymyxin B was approved for medical use in 1964 in the United States. 

POLY MXB 5,00,000 IU INJECTION USES ?

Polymyxin B injection is an antibiotic used to treat bacterial infections (meningitis, pneumonia, sepsis, and urinary tract infections). 

WHAT ARE THE SIDE-EFFECTS OF POLYMYXIN B 5,00,000 IU INJECTION ?

Check with your doctor or nurse immediately if any of the following side effects occur:

Dizziness, drowsiness, fever, headache, numbness or tingling in hands or feet, pain in the lower back or side, shakiness and unsteady walk, stiff neck, unsteadiness, trembling, or other problems with muscle control or coordination. 

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects.