OTIDE Octreotide Injection

Otide
100Mcg Injection is a somatostatic agent. It is used to treat severe cases of
diarrhea, flushes and types of cancer. It functions by
decreasing the blood levels of hormones and chemical messengers. It is sold
under the trade name of Sandostatin.

MEDICINE USES:

Otide Injection is used for
Overproduction of growth hormone, Abnormal growth of hands, Feet and face,
Chronic liver disease, Gastro-entero-pancreatic endocrine
tumors, Pituitary tumors, Complications following pancreatic
surgery and other conditions. Otide Injection
may also be used for purposes not listed in this medication guide.

Otide Injection contains Octreotide as an active ingredient.

Otide Injection works by
inhibiting increased secretion of growth hormones.

United Biotech manufactures
Otide Injection.

OTIDE COMMON SIDE EFFECT:

The following is a list of possible side-effects that may occur from all constituting ingredients of Otide
Injection. This is not a comprehensive list. These
side-effects are possible, but do not always occur. Some of the side-effects
may be rare but serious. Consult your doctor if you observe any of the
following side-effects, especially if they do not go away.

Hypoglycaemia,Abdominal
bloating,Hyperglycemia,Alopecia,Nausea,Biliary
sludge,Otide
Injection may also cause side-effects not listed here.

OTIDE INJECTION-PRECAUTIONS:

Before using Otide Injection,
inform your doctor about your current list of medications, over the counter
products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing
diseases, and current health conditions (e.g. pregnancy, upcoming surgery,
etc.). Some health conditions may make you more susceptible to the side-effects
of the drug. Take as directed by your doctor or follow the direction printed on
the product insert. Dosage is based on your condition. Tell your doctor if your
condition persists or worsens. Important counseling points are listed below.

Avoid
taking this medicine if you are pregnant or breastfeeding

Consult
your doctor before if consuming any medicine for blood pressure

Do not
drive or operate heavy machinery

Monitor
the functioning of thyroid and liver.

OTIDE
INJECTION- DRUG INTERACTIONS:

If you use other drugs or over the counter products at the
same time, the effects of Otide Injection may change.
This may increase your risk for side-effects or cause your drug not to work
properly. Tell your doctor about all the drugs, vitamins, and herbal
supplements you are using, so that you doctor can help you prevent or manage
drug interactions. Otide Injection may
interact with the following drugs and products:

Bromocriptine,Cabergoline,Cimetidine,Cyclosporine
A,Human
Insulin,Insulin
Lispro.

Medicine Specifications:-

Brand Name: Ovipure HP-5000
Composition : Human Chorionic Gonadotrophin 5000 I.U
Manufacturer: Bharat Serums and Vaccines Limited
Form: Injection
Strength: 5000 I.U
Packing: Pack of 1 vial of 1mL/2mL
Storage: 2- 8°C

产品介绍:

哌柏西利（Palbociclib，又译为：帕博西尼）是全球首个细胞周期蛋白依赖性激酶（CDK）4/6抑制剂，适用于治疗激素受体（HR）阳性、人表皮生长因子受体2（HER2）阴性的局部晚期或转移性乳腺癌，应与芳香化酶抑制剂联合使用作为绝经后女性患者的初始内分泌治疗。

乳腺癌是严重威胁全世界女性健康的第一大恶性肿瘤，晚期乳腺癌的形势更为严峻，总体中位生存期仅有2-3年，5年生存率仅约20%。

CDK4/6抑制剂是近年来热门的抗癌“神药”，正在迅速改变HR + HER2-晚期乳腺癌的治疗格局，有效地克服或延迟内分泌抵抗的出现，为晚期患者争取更多的生存时间。

基于II期研究PALOMA-1，2015年2月3日美国FDA加速批准了哌柏西利联合来曲唑用于绝经后 ER+/HER2-晚期乳腺癌的一线治疗。2016年2月19日美国FDA根据一项随机对照III期研究（PALOMA-3）又批准了哌柏西利联合氟维司群用于既往内分泌治疗失败的HR+/HER2- 绝经后晚期乳腺癌。

由于优秀的疗效及安全性，哌柏西利至今已在全球80多个国家和地区获批上市。2018年7月31日，中国药监局批准了该药在华上市，是哌柏西利第87个获准上市的国家，也是中国10年来晚期乳腺癌唯一突破性创新疗法，因此备受关注。

碧康制药生产的Palbonix是哌柏西利是获得孟加拉政府监管机构批准合法生产的仿制药。

碧康制药由欧洲财团参与投资，是南亚地区唯一执行欧盟技术规范，并且在孟加拉两大证券交易所主板上市的大型制药企业，产品符合欧洲药典和美国药典标准。

相比其他来源不清晰的所谓同一种仿制药，即使其主要成份含量与碧康产品相接近，但由于不具备严格规范的GMP标准生产场所和政府部门的严格监管，其产品中影响药物吸收率的溶出度和生物利用度也与碧康产品具有很大差异。

为保证用药安全，敬请谨慎选择！

适应症:

用于激素受体（HR）阳性，人表皮生长因子受体2（EFGR2）阴性的进展性或转移性乳腺癌，可联合用于以下情形：

1、与来曲唑联用，用于治疗绝经后女性患者的雌激素受体阳性（ER+）及人表皮生长因子受体阴性(Her2)的晚期乳腺癌；

2、联合氟维司群，用于既往内分泌治疗失败的HR/Her2绝经后晚期乳腺癌。

用法与用量:

推荐起始剂量为每日1次，每次125 mg，与来曲唑联合使用，与餐同服，共21天，之后停止服药7天。

 特殊人群的使用：

哺乳妇女停药或停止哺乳。

 常见副作用：

最常见的不良反应（发生率≥10％）为白细胞减少，白细胞减少，乏力，贫血，上呼吸道感染，恶心，口腔炎，脱发，腹泻，血小板减少症，食欲下降，呕吐，无力，周围神经病变，和鼻出血。

Palboxen(Palbociclib) is the generic name for the trade name drug Ibrance. In some cases, health care professionals may use the trade name Ibrance when referring to the generic drug name palbociclib. Palbociclib is used in combination with letrozole (an aromatase inhibitor) to treat postmenopausal women with estrogen receptor (ER) positive, HER2 negative advanced breast cancer.

Palboxen(Palbociclib) 是商品名药物 Ibrance 的通用名称。在某些情况下，医疗保健专业人员在提及通用药物名称 palbociclib 时可能会使用商品名 Ibrance。 Palbociclib 与来曲唑（一种芳香化酶抑制剂）联合用于治疗雌激素受体（ER）阳性、HER2 阴性晚期乳腺癌的绝经后妇女。

Neocuron Injection Details:

Brand Name    : Neocuron Injection
Content            : Pancuronium Bromide
Manufacturer : Neon Laboratories Ltd.
Strength          : 4 mg/ 2 ml