Ibrutinib 140mg Capsule Brands
Brand Name: Ibrutinib
International Brand Name: Imbruvica
Other Name: PCI-32765, CRA-032765
Active Ingredient: Ibrutinib
Available Brands: Ibrunat, Imbruvica, Ibrutix, Ibruxen, Ibrucent, Lucibru, etc.
Ibrutinib 140mg Capsule Description:
Ibrutinib 140mg is a targeted therapy. It inhibits the function of Bruton's tyrosine kinase (BTK). BTK is a key signaling molecule of the B-cell receptor signaling complex that plays an important role in the survival of malignant B cells. It blocks signals that stimulate malignant B cells to grow and divide uncontrollably. It is not a chemotherapy drug but one of what are termed "targeted therapies."
Anticancer Drugs - Kinase Inhibitors
Ibrutinib Capsules Indian Imbruvica Brands India :
Ibrunat Capsules by Natco Pharma
Nitib by Hetero Oncology
Ibrushil by Shilpa Medicare
How Generic Imbruvica Capsules Works?
Ibrutinib is an inhibitor of Bruton’s tyrosine kinase (BTK). It forms a covalent bond with a cysteine residue in the active site of BTK (Cys481), leading to its inhibition. The inhibition of BTK plays a role in the B-cell receptor signaling and thus, the presence of ibrutinib prevents the phosphorylation of downstream substrates such as PLC-γ.
Side Effects of Indian Ibrutinib Capsules
Report to the physician immediately if the patients are having any of these following symptoms:
- Fever, chills, body aches
- Feeling tired
- Bruising or increased tendency of bruising
- Mouth sores
- Nausea & vomiting
- Skin rash
- Joint pain & muscle cramps
- Low platelets
- Swollen hands, ankles or feet
- High blood pressure
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