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Ibrutinib 140mg Capsule Brands

Ibrutinib 140mg Capsule Description:

Ibrutinib 140mg is a targeted therapy. It inhibits the function of Bruton's tyrosine kinase (BTK). BTK is a key signaling molecule of the B-cell receptor signaling complex that plays an important role in the survival of malignant B cells. It blocks signals that stimulate malignant B cells to grow and divide uncontrollably. It is not a chemotherapy drug but one of what are termed "targeted therapies."

Therapeutic Class

Anticancer Drugs - Kinase Inhibitors

Ibrutinib Capsules Indian Imbruvica Brands India : 

Ibrunat Capsules by Natco Pharma

Nitib by Hetero Oncology

Ibrushil by Shilpa Medicare

How Generic Imbruvica Capsules Works?

Ibrutinib is an inhibitor of Bruton’s tyrosine kinase (BTK). It forms a covalent bond with a cysteine residue in the active site of BTK (Cys481), leading to its inhibition. The inhibition of BTK plays a role in the B-cell receptor signaling and thus, the presence of ibrutinib prevents the phosphorylation of downstream substrates such as PLC-γ.

Side Effects of Indian Ibrutinib Capsules

Report to the physician immediately if the patients are having any of these following symptoms:

  • Fever, chills, body aches
  • Feeling tired
  • Bruising or increased tendency of bruising
  • Mouth sores
  • Headache
  • Constipation
  • Nausea & vomiting
  • Diarrhoea
  • Skin rash
  • Joint pain & muscle cramps
  • Low platelets
  • Swollen hands, ankles or feet
  • High blood pressure

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Tags: Ibrutinib, Imbruvica, b-cell cancer, natco, anti-cancer, PCI-32765, CRA-032765, Leukemia