What is Acabrunat 100mg Capsule ?

Acabrunat 100mg Capsules Generic Acalabrutinib is a prescription medicine used to treat Mantle cell lymphoma (MCL) who have received at least one treatment for their cancer, or Chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).

Indian Acalabrutinib Capsules Side Effects:

The most common adverse reactions (incidence rate ≥ 30%) are

Anemia, neutropenia, upper respiratory tract infection, thrombocytopenia, headache, diarrhea, and skeletal muscle pain.

The above information comes from the Internet. Please consult with the doctor for medical advice.

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WHAT IS ACITROM TABLETS?

Acitrom 1mg Tablet is a medicament to prevent blood clots which might be harmful and even fatal, thereby reducing the chances of stroke and cardiac arrest. It helps in increasing and catalyzing blood flow in the body by reducing the amount of blood clotting proteins in the blood stream. In simple term it is an anti-coagulant also known as blood thinner and belongs to semi synthetic origin. 

USES OF ACITROM TABLETS:

Acitrom Tablet is used for Prevention or treatment of blood clotting, Blood clots in blood vessels, Deep venous thrombosis, Artificial heart valves, Artificial heart valve, Pulmonary embolism, Atrial fibrillation, Post heart attack and other conditions. Acitrom Tablet may also be used for purposes not listed in this medication guide.

Acitrom Tablet contains Acenocoumarol as an active ingredient.

Acitrom Tablet works by inhibiting the formation of blood clots.

POSSIBLE SIDE EFFECTS:

The most commonly reported side-effects of Acitrom Tablet are unexplained bruising, bleeding, coughing or vomitting blood, dizziness, bloody or black stools, and blood in the urine or farces.

COMMON SIDE EFFECTS MAY INCLUDE:

The following is a list of possible side effects that may occur from the use of Acitrom Tablet. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.

Unexplained bruising

Bleeding

Coughing or vomitting blood

Dizziness

Bloody or black stools

Blood in the urine or faeces

Inflammation of skin

Blood in urine

Urge to vomit

Joint pain

Internal bleeding

Back pain

Skin inflammation

Coughing or vomiting blood

Heavy bleeding from cuts or wounds

Arthralgia

Chronic headache

Nose bleeding

Diarrhoea

DRUGS PRECAUTIONS:

Before using Acitrom Tablet, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.

Deficiency in protein C or S

Disorder affecting the absorption of food from the stomach

Exercise caution in case of elderly patients

Infections

Inflammation

Kidney disease

Limit alcohol consumption

Liver disease

Procedures causing bleeding

Severe heart failure

Taking consistent levels of Vitamin K rich food

Thyroid gland disease

Tumors

DRUGS INTERACTIONS:

If you use other drugs or over the counter products at the same time, the effects of Acitrom Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Acitrom Tablet may interact with the following drugs and products:

Acenocoumarol may potentiate the risk of toxicity by phenytoin.

Aminoglutethimide, Azathioprine, 6-mercaptopurine, Ritonavir, Nelfinavir, Phenobarbital, Carbamazepine, Cholestyramine, Griseofulvin, Oral contraceptives, Rifampicin, Saint John’s wort, Foods rich in Vitamin K decrease the effects of Acenocoumarol.

Heparin, Antibiotics, Salicylic acid, Diflunisal, Clopidogrel, Ticlopidine, Phenylbutazone, Sulfinpyrazone, Sulfinpyrazone, Non-steroidal anti-inflammatory agents, Allopurinol, Androgens, Anabolic steroids, Antiarrhythmic agents, Citalopram, Fluoxetine, Sertraline, Cimetidine, Clofibrate, Corticosteroids, Disulfiram, and Ethacrynic acid, Glucagon, Paracetamol, Sulfonylurea derivatives, Thyroid hormones, Statins, Tamoxifen, Proton pump inhibitors, Plasminogen activators, Thrombin inhibitors, Prokinetic agents, Antacids, Vitamin E increase the activity of Acenocoumarol.

ABOUT EXEMPTIA INJECTION

Exemptia Adalimumab injection is a potent
TNF-inhibitor and anti-inflammatory drug manufactured by Zydus Cadila. It binds
to tumor necrosis factor-alpha (TNFα). TNFα normally binds to TNFα receptors,
which leads to the inflammatory response of autoimmune diseases. By binding to
TNFα, Exemptia reduces this inflammatory response. The TNF-inhibitor affects
the body’s defense system, i.e. the immune system that protects the body from
infection.

MEDICINAL USES

Exemptia 40 mg prefilled syringe is used to treat certain types of arthritis
(inflammatory disorder that typically affects the small joints in hands and
feet) including:

Ulcerative colitis: Disease that causes ulcers on the lining of the large gut.

Crohn’s Disease: Serious inflammation of gastrointestinal tract.

heumatoid
arthritis (RA): It is a long-lasting autoimmune disease that causes pain,
swelling, stiffness and loss of function in your joints. It can affect any
joint but is common in the wrist and fingers.

Psoriatic arthritis: It happens because your immune system is overactive. It
affects mostly people who have psoriasis, a skin disease that’s also related to
the immune system.

Ankylosing
spondylitis : An inflammatory arthritis affecting the spine and large joints.

Plaque psoriasis: Plaque psoriasis is a chronic autoimmune condition. It
appears on the skin in patches of thick, red, scaly skin.

Juvenile
idiopathic arthritis : Juvenile idiopathic arthritis (JIA), also known as
juvenile rheumatoid arthritis (JRA) is currently the most widely accepted term
to describe various types of chronic arthritis in children.

EXEMPTIA INJECTION SIDE EFFECTS:

The following is a list of common side effects that may occur
from the use of Exemptia Prefilled Syringe Powder. This is not a comprehensive
list. Consult your doctor if you observe any of the following side effects,
especially if they do not go away.

Fever , Headache , Acne , Chest pain , Nausea , Abdominal
pain , Sinusitis , Confusion , Dehydration , Back pain , Allergic respiratory
symptoms , Rise in blood lipid level , Pain at injection site , Urinary  tract infection etc.

EXEMPTIA INJECTION PRECAUTIONS:

Adalimumab is given by an injection under the skin. Your
pharmacist will tell you how often to take an injection of Exemptia. Do not try
to inject it yourself until you have been shown the right way to give the
injections and have read and understood this Instructions for Use.

·        
Change
the injection site each time to lessen injury under the skin.

·        
Do not
inject into any areas of the skin that are sore, bruised, red, or hard.

·        
Do not
increase your dose or use this drug more often or for longer than prescribed.

·        
Do not
have immunizations/vaccinations without the consent of your doctor.

·        
Avoid
contact with people who have recently received live vaccines (such as flu
vaccine inhaled through the nose).

·        
Before
using Adalimumab 40mg injection, tell your doctor or pharmacist if you are
suffering from any major diseases, especially of: current/recent/repeated
infections (such as hepatitis B, TB infection, histoplasmosis), blood/bone
marrow problems , seizures, cancer, heart disease (especially heart failure)
etc.

·        
Do not
use this Arthritis drug for a condition for which it was not prescribed. It may
be harmful for you.

·        
During
pregnancy, this medication should be used only when clearly needed.

·        
Discuss
the risks and benefits with your doctor.Inform your doctor, if you are
breastfeeding. The medicine may pass into your breast milk and could be harmful
to the baby.

·        
You and
your physician should decide if you will breastfeed or use Adalimumab
Injection. You should not do both.

 

STORAGE REQUIREMENTS:

Store at 2°C to 8°C (36°F to 46°F) in original container; do
not freeze. Do not use if frozen even if it has been thawed. Do not store in
extreme heat or cold. Protect from light. Keep Exemptia injection and all other
medicines out of the reach of children.

Exemptia Adalimumab injection is a potent TNF-inhibitor and anti-inflammatory drug manufactured by Zydus Cadila. It binds to tumor necrosis factor-alpha (TNFα). TNFα normally binds to TNFα receptors, which leads to the inflammatory response of autoimmune diseases. By binding to TNFα, Exemptia reduces this inflammatory response. The TNF-inhibitor affects the body’s defense system, i.e. the immune system that protects the body from infection.
USES

Exemptia 40 mg prefilled syringe is used to treat certain types of arthritis (inflammatory disorder that typically affects the small joints in hands and feet) including –

    Ulcerative colitis : Disease that causes ulcers on the lining of the large gut.
    Crohn’s Disease : Serious inflammation of gastrointestinal tract.
    Rheumatoid arthritis (RA) : It is a long-lasting autoimmune disease that causes pain, swelling, stiffness and loss of function in your joints. It can affect any joint but is common in the wrist and fingers.
    Psoriatic arthritis : It happens because your immune system is overactive. It affects mostly people who have psoriasis, a skin disease that’s also related to the immune system.
    Ankylosing spondylitis : An inflammatory arthritis affecting the spine and large joints.
    Plaque psoriasis : Plaque psoriasis is a chronic autoimmune condition. It appears on the skin in patches of thick, red, scaly skin.
    Juvenile idiopathic arthritis : Juvenile idiopathic arthritis (JIA), also known as juvenile rheumatoid arthritis (JRA) is currently the most widely accepted term to describe various types of chronic arthritis in children.

EXEMPTIA COMMON SIDE EFFECTS :

The following is a list of common side effects that may occur from the use of Exemptia Prefilled Syringe Powder. This is not a comprehensive list. Consult your doctor if you observe any of the following side effects, especially if they do not go away.

Fever , Headache , Acne , Chest pain , Nausea , Abdominal pain , Sinusitis , Confusion , Dehydration , Back pain , Allergic respiratory symptoms , Rise in blood lipid level , Pain at injection site , Urinary tract infection etc.

SAFETY INFORMATION (Precautions) :

    Adalimumab is given by an injection under the skin. Your pharmacist will tell you how often to take an injection of Exemptia. Do not try to inject it yourself until you have been shown the right way to give the injections and have read and understood this Instructions for Use.
    Do not share Exemptia prefilled syringe to other people, even if they have the same condition.
    Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin. Do not inject into any areas of the skin that are sore, bruised, red, or hard.
    Do not increase your dose or use this drug more often or for longer than prescribed.
    Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).
    Before using Adalimumab 40mg injection, tell your doctor or pharmacist if you are suffering from any major diseases, especially of: current/recent/repeated infections (such as hepatitis B, TB infection, histoplasmosis), blood/bone marrow problems , seizures, cancer, heart disease (especially heart failure) etc.
    Do not use this Arthritis drug for a condition for which it was not prescribed. It may be harmful for you.
    During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
    Inform your doctor, if you are breastfeeding. The medicine may pass into your breast milk and could be harmful to the baby. You and your physician should decide if you will breastfeed or use Adalimumab Injection. You should not do both.

PROPER STORAGE OF EXEMPTIA :

Store at 2°C to 8°C (36°F to 46°F) in original container; do not freeze. Do not use if frozen even if it has been thawed. Do not store in extreme heat or cold. Protect from light. Keep Exemptia injection and all other medicines out of the reach of children.