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Sotoxen Sotorasib Tablet Everest

Sotoxen Sotorasib Tablet Everest

Brand Name: Sotoxen

Active Ingredient: Sotorasib

International Trade Name: Lumakras

Manufacturer: Everest Pharma

Strength: 120 mg

Form: Tablets

Packing: Pack of 56 Tablets

Not for Sale in India

Product Description

Sotorasib Tablet Generic Lumakras:

Sotoxen (Sotorasib), generic Lumakras is a prescription medicine used to treat metastatic non-small cell lung cancer.

Sotorasib, also known as AMG-510, is an acrylamide-derived KRAS inhibitor developed by Amgen. It is indicated in the treatment of adult patients with non-small cell lung cancer with the KRAS G12C mutation. This mutation accounts for >50% of all KRAS mutations.

索托拉昔布

KRASG12C抑制剂,sotorasib上市,用于治疗既往至少接受过一次系统治疗的携带KRASG12C突变局部晚期或转移性非小细胞肺癌(NSCLC)患者。这是全球首个获得批准的靶向KRAS突变的肿瘤治疗药物。


AMG510是什么药物?

AMG510是KRAS的抑制剂G12C系列,一种肿瘤限制性,突变致癌形式的RAS GTP酶,KRAS。AMG510与KRAS的独特半胱氨酸形成不可逆的共价键G12C系列,将蛋白质锁定在非活性状态,以防止下游信号传导而不影响野生型KRAS。AMG510阻断KRAS信号传导,抑制细胞生长,并仅在KRAS G12C肿瘤细胞系中促进细胞凋亡。AMG510抑制KRASG12C系列在体外和体内,可检测的脱靶活性最小。在小鼠肿瘤异种移植模型中,AMG510治疗导致肿瘤消退和生存期延长,并且在KRAS G12C模型中与抗肿瘤免疫有关。


Dosage of Sotorasib Generic Lumakras Tablet:

Recommended dose: 960 mg orally once daily.

Take 1 time a day, around the same time.

Can be taken with or without food.

Swallow the tablet whole, do not chew, crush or break the tablet.


Side Effects of Generic Lumakras Tablet:

The most common side effects are:

Nausea, vomiting, diarrhea or constipation, muscle/ joint pain, or tiredness.


FAQ about Sotoxen (Sotorasib)/ Lumakras Generic Sotorasib:

Q. Is Sotoxen (Sotorasib)/ Lumakras Generic Sotorasib available to supply worldwide?

Yes! We can supply Sotoxen (Sotorasib) worldwide. We can supply our prescription medicine in most of the country for patient’s personal use.


Q. What’s the Sotoxen (Sotorasib)/ Lumakras Generic Sotorasib minimum order quantity?

Minimum quantity order of Sotoxen (Sotorasib) depends on client/ patients demand. We’ll notify it after price inquiring.


Q. How I can order Sotoxen (Sotorasib)/ Lumakras Generic Sotorasib?

To order this Sotoxen (Sotorasib), please inquiry the price first with proper information and then add to cart.


Buy Sotoxen Sotorasib Tablet at Wholesale Price from India : Generic Lumakras Supplier LetsMeds

LetsMeds online pharmacy helps patients receive high-quality medicines at the lowest prices worldwide. Our reputation has been formed thanks to long-term and trusting relationships with customers, excellent service and pricing policy. We believe that all our clients should receive high-tech and affordable oncological medicines now.  If you wish to order Generic Sotorasib Everest and send them overseas you just need to fill the "Ask For Price" form and contact us. We will get in touch with you shortly as your order gets placed.

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