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WHAT IS ROLIMUS TABLETS ?
Rolimus is an immunosuppressant. It works by blocking the action of certain blood cells in the immune system that may cause the body to reject the transplanted organ.
AFINITOR TABLET USES :
Rolimus is used with other medications (such as cyclosporine) to prevent rejection of a kidney transplant. Everolimus Tablets are also used with other medications (such as tacrolimus) to prevent rejection of a liver transplant.
EVEROLIMUS TABLETS COMMON SIDE EFFECTS :
Constipation, headache, nausea, and sores in the mouth/throat may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Tell your doctor right away if you have any serious side effects, including: swelling hands/ankles/feet, wound problems (such as infection, slow wound healing, the opening of the wound), decreased sexual ability (in men), chest pain/pressure, shortness of breath, unusual bruising/bleeding.
Everolimus may cause your cholesterol/triglycerides or blood sugar to increase.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
SAFETY INFORMATION (Precautions) for ROLIMUS EVEROLIMUS TABLETS :
- Before taking everolimus, tell your doctor or pharmacist if you are allergic to it, or to sirolimus or temsirolimus; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
- Before using this medication, tell your doctor or pharmacist your medical history, especially of: high cholesterol/triglyceride levels, any recent/current infections, diabetes, liver disease, certain hereditary enzyme problems (galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption).
- Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).
- Since this medication may increase your risk of skin cancer, avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors.
- Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while you are taking everolimus. The medicine may harm an unborn baby. Ask about reliable forms of birth control while taking this medication and for 8 weeks after stopping treatment. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication.
- It is unknown if this medication passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug and for 2 weeks after stopping treatment is not recommended. Consult your doctor before breast-feeding.
MEDICATION STORAGE REQUIREMENTS :
Store at room temperature of 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Protect from light; protect from moisture.
MEDICINE INTERACTIONS :
Some products that may interact with this drug include: other drugs that weaken the immune system/increase the risk of infection (such as natalizumab, rituximab), ACE inhibitors (such as captopril, lisinopril).
Other medications can affect the removal of everolimus from your body, which may affect how everolimus works. Examples include :
- azole antifungals (such as itraconazole, ketoconazole),
- macrolide antibiotics (such as clarithromycin, erythromycin),
- HIV protease inhibitors (such as atazanavir, ritonavir),
- rifamycins (such as rifabutin, rifampin),
- St. John's wort, telaprevir, telithromycin, among others.
This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.