ABOUT EXEMPTIA INJECTION

Exemptia Adalimumab injection is a potent TNF-inhibitor and anti-inflammatory drug manufactured by Zydus Cadila. It binds to tumor necrosis factor-alpha (TNFα). TNFα normally binds to TNFα receptors, which leads to the inflammatory response of autoimmune diseases. By binding to TNFα, Exemptia reduces this inflammatory response. The TNF-inhibitor affects the body’s defense system, i.e. the immune system that protects the body from infection.

MEDICINAL USES

Exemptia 40 mg prefilled syringe is used to treat certain types of arthritis (inflammatory disorder that typically affects the small joints in hands and feet) including:
Ulcerative colitis: Disease that causes ulcers on the lining of the large gut.
Crohn’s Disease: Serious inflammation of gastrointestinal tract.

heumatoid arthritis (RA): It is a long-lasting autoimmune disease that causes pain, swelling, stiffness and loss of function in your joints. It can affect any joint but is common in the wrist and fingers.
Psoriatic arthritis: It happens because your immune system is overactive. It affects mostly people who have psoriasis, a skin disease that's also related to the immune system.

Ankylosing spondylitis : An inflammatory arthritis affecting the spine and large joints.
Plaque psoriasis: Plaque psoriasis is a chronic autoimmune condition. It appears on the skin in patches of thick, red, scaly skin.

Juvenile idiopathic arthritis : Juvenile idiopathic arthritis (JIA), also known as juvenile rheumatoid arthritis (JRA) is currently the most widely accepted term to describe various types of chronic arthritis in children.

EXEMPTIA INJECTION SIDE EFFECTS:

The following is a list of common side effects that may occur from the use of Exemptia Prefilled Syringe Powder. This is not a comprehensive list. Consult your doctor if you observe any of the following side effects, especially if they do not go away.

Fever , Headache , Acne , Chest pain , Nausea , Abdominal pain , Sinusitis , Confusion , Dehydration , Back pain , Allergic respiratory symptoms , Rise in blood lipid level , Pain at injection site , Urinary  tract infection etc.

EXEMPTIA INJECTION PRECAUTIONS:

Adalimumab is given by an injection under the skin. Your pharmacist will tell you how often to take an injection of Exemptia. Do not try to inject it yourself until you have been shown the right way to give the injections and have read and understood this Instructions for Use.

·         Change the injection site each time to lessen injury under the skin.

·         Do not inject into any areas of the skin that are sore, bruised, red, or hard.

·         Do not increase your dose or use this drug more often or for longer than prescribed.

·         Do not have immunizations/vaccinations without the consent of your doctor.

·         Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).

·         Before using Adalimumab 40mg injection, tell your doctor or pharmacist if you are suffering from any major diseases, especially of: current/recent/repeated infections (such as hepatitis B, TB infection, histoplasmosis), blood/bone marrow problems , seizures, cancer, heart disease (especially heart failure) etc.

·         Do not use this Arthritis drug for a condition for which it was not prescribed. It may be harmful for you.

·         During pregnancy, this medication should be used only when clearly needed.

·         Discuss the risks and benefits with your doctor.Inform your doctor, if you are breastfeeding. The medicine may pass into your breast milk and could be harmful to the baby.

·         You and your physician should decide if you will breastfeed or use Adalimumab Injection. You should not do both.

 

STORAGE REQUIREMENTS:

Store at 2°C to 8°C (36°F to 46°F) in original container; do not freeze. Do not use if frozen even if it has been thawed. Do not store in extreme heat or cold. Protect from light. Keep Exemptia injection and all other medicines out of the reach of children.

Exemptia Adalimumab injection is a potent TNF-inhibitor and anti-inflammatory drug manufactured by Zydus Cadila. It binds to tumor necrosis factor-alpha (TNFα). TNFα normally binds to TNFα receptors, which leads to the inflammatory response of autoimmune diseases. By binding to TNFα, Exemptia reduces this inflammatory response. The TNF-inhibitor affects the body’s defense system, i.e. the immune system that protects the body from infection.
USES

Exemptia 40 mg prefilled syringe is used to treat certain types of arthritis (inflammatory disorder that typically affects the small joints in hands and feet) including -

    Ulcerative colitis : Disease that causes ulcers on the lining of the large gut.
    Crohn’s Disease : Serious inflammation of gastrointestinal tract.
    Rheumatoid arthritis (RA) : It is a long-lasting autoimmune disease that causes pain, swelling, stiffness and loss of function in your joints. It can affect any joint but is common in the wrist and fingers.
    Psoriatic arthritis : It happens because your immune system is overactive. It affects mostly people who have psoriasis, a skin disease that's also related to the immune system.
    Ankylosing spondylitis : An inflammatory arthritis affecting the spine and large joints.
    Plaque psoriasis : Plaque psoriasis is a chronic autoimmune condition. It appears on the skin in patches of thick, red, scaly skin.
    Juvenile idiopathic arthritis : Juvenile idiopathic arthritis (JIA), also known as juvenile rheumatoid arthritis (JRA) is currently the most widely accepted term to describe various types of chronic arthritis in children.

EXEMPTIA COMMON SIDE EFFECTS :

The following is a list of common side effects that may occur from the use of Exemptia Prefilled Syringe Powder. This is not a comprehensive list. Consult your doctor if you observe any of the following side effects, especially if they do not go away.

Fever , Headache , Acne , Chest pain , Nausea , Abdominal pain , Sinusitis , Confusion , Dehydration , Back pain , Allergic respiratory symptoms , Rise in blood lipid level , Pain at injection site , Urinary tract infection etc.

SAFETY INFORMATION (Precautions) :

    Adalimumab is given by an injection under the skin. Your pharmacist will tell you how often to take an injection of Exemptia. Do not try to inject it yourself until you have been shown the right way to give the injections and have read and understood this Instructions for Use.
    Do not share Exemptia prefilled syringe to other people, even if they have the same condition.
    Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin. Do not inject into any areas of the skin that are sore, bruised, red, or hard.
    Do not increase your dose or use this drug more often or for longer than prescribed.
    Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).
    Before using Adalimumab 40mg injection, tell your doctor or pharmacist if you are suffering from any major diseases, especially of: current/recent/repeated infections (such as hepatitis B, TB infection, histoplasmosis), blood/bone marrow problems , seizures, cancer, heart disease (especially heart failure) etc.
    Do not use this Arthritis drug for a condition for which it was not prescribed. It may be harmful for you.
    During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
    Inform your doctor, if you are breastfeeding. The medicine may pass into your breast milk and could be harmful to the baby. You and your physician should decide if you will breastfeed or use Adalimumab Injection. You should not do both.

PROPER STORAGE OF EXEMPTIA :

Store at 2°C to 8°C (36°F to 46°F) in original container; do not freeze. Do not use if frozen even if it has been thawed. Do not store in extreme heat or cold. Protect from light. Keep Exemptia injection and all other medicines out of the reach of children.