What is Osimertinib Tablet?
Osimertinib – Overview of Usage, Dosage, Side Effects, Warnings, and Precautions
Osimertinib is a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug. It treats metastatic non-small lung cancer (NSLC), showing positive EGFR expression. Osimertinib, being an EGFR-TKI, is found to be effective in at least 10 % of patients having lung cancer due to the presence of EGFR mutations in the tumor cells. The development of Osimertinib, a third-generation EGFR-TKI, shows alteration in tumor resistance patterns and side effects when administered that impact the quality of life. The use of first-generation EGFR-TKI is found to develop resistance by activating the EGFR gene mutations. And the second-generation EGFR-TKI is proven to be a potent inhibitor. However, the nonspecific targeting of EGFR leads to increased toxicity. But, third-generation drugs like Osimertinib are specific to certain mutations, thereby reducing non-specific binding and minimizing the chances of toxicity.
Dosage of Indian Osimertinib 80mg Tablet
The dosage of Osimertinib is typically determined by a healthcare provider based on individual factors, including the patient’s condition, response to treatment, and presence of any other medical issues. It is important to follow the prescribed dosage instructions and not to alter the dosage without consulting your healthcare provider.
Side Effects of Osimertinib 80 mg Tablet
Common side effects of Osimertinib may include diarrhea, rash, dry skin, nausea, and fatigue. In some cases, more severe side effects can occur, such as lung or heart complications, which may require immediate medical attention. If any side effects are persistent or worsen, it is essential to contact your healthcare provider.
What You Should Know About Lung Cancer?
The lungs are vital respiratory organs responsible for inhaling oxygen and exhaling carbon dioxide. Smoking significantly increases the risk of developing lung cancer, which is the leading cause of cancer-related deaths globally. However, lung cancer can also affect individuals who have never smoked, as exposure to secondhand smoke is another contributing factor.
Common signs and symptoms of lung cancer include shortness of breath, chest pain, coughing up blood, unexplained weight loss, headaches, and bone pain. There are two main types of lung cancer: small cell lung cancer and non-small cell lung cancer, each with distinct characteristics and treatment approaches.
Frequently Asked Questions
1. Does Osimertinib Belong to Chemotherapy?
Osimertinib is a member of a class of drugs known as antineoplastics (cancer medicines). It is a targeted therapy drug. Targeted therapies are not immunotherapy or chemotherapy. It prevents the development of cancer cells, which are subsequently eliminated.
2. How Long Is Osimertinib Safe to Take?
Osimertinib is designed to be taken over an extended period for some applications. You will probably use Osimertinib for an extended period if you and your doctor decide it is safe and beneficial. Osimertinib may be taken for up to three years when prescribed as adjuvant therapy after surgery. After that, you can take Osimertinib for other purposes until you can no longer tolerate its side effects. Alternatively, you may continue taking Osimertinib until the cancer treatment has been stopped.
3. Does Osimertinib Cause Fatigue?
Most people have very few or no side effects at all. However, one might experience constipation, diarrhea, nausea, mouth sores, dry or itchy skin, fatigue, headache, back pain, or loss of appetite. These mild impacts usually resolve within a few days to a few weeks. However, if they start to bother you, consult your doctor or pharmacist.
4. What Is the Recommended Time to Take Osimertinib?
The medication should be taken at roughly the same time each day. This helps maintain the medical level consistently in the body. If you forget to take a dose, skip it and resume your regular schedule. Never take additional doses or two doses at once.
5. How Soon Does Osimertinib Start to Work?
The only first-line therapy for non-small cell lung cancer with EGFR (epidermal growth factor receptor) mutations that has a median overall survival of more than three years is Osimertinib. Osimertinib begins to work as the first dose is taken. To monitor how well the drug treats cancer, the doctor will prescribe several scans and tests throughout the treatment.
6. Can Osimertinib Cause Hair Loss?
Osimertinib might result in hair loss. Despite being rare, hair loss did occur in studies of drug users. Drugs used for targeted therapy may result in graying and thinning of the hair on the arms and legs, and hair loss. Additionally, it may cause an increase in the thickness and curl of eyebrows, eyelashes, and facial hair.
7. Is It Safe to Drink Alcohol With Osimertinib?
Alcohol consumption (in moderation) does not seem to impact Osimertinib’s efficacy or safety. Osimertinib and alcohol are known not to interact. However, drinking may result in some of the same frequent side effects as Osimertinib. These include nausea, discomfort in the abdomen, and vertigo. If you consume alcohol, discuss with your doctor what is the safe limit for consumption or whether it is safe to consume while receiving treatment.
8. What Is EGFR TKI?
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) are the first-line therapy in treating non-small cell lung cancer harboring EGFR-sensitive mutations. They are a type of targeted therapy. TKIs are taken orally as pills. A targeted therapy lessens the harm to healthy cells by identifying and attacking particular cancer cell types.
9. Which Medications Are EGFR Inhibitors?
Epidermal growth factor receptor inhibitors used in non-small cell lung cancer with EGFR gene mutations include:
– Erlotinib
– Afatinib
– Gefitinib
– Osimertinib
– Dacomitinib
Osimertinib 80 mg (AZD9291) Tablets in the Philippines – Available in Various Cities
Osimertinib 80 mg, also known as AZD9291, is a targeted therapy medication for non-small cell lung cancer (NSCLC) with specific genetic mutations. In the Philippines, Osimertinib is accessible through LetsMeds Pharmaceuticals, which focuses on making the medication affordable and widely available across the country.
LetsMeds offers Osimertinib 80 mg with delivery services in major cities, including but not limited to:
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Disclaimer:
The information provided here is for general informational purposes only and should not be considered as medical advice. Osimertinib 80 mg (AZD9291) is a prescription medication and should only be used under the supervision of a qualified healthcare provider. Consult your doctor or pharmacist for specific medical advice, including proper diagnosis, treatment options, and potential side effects. Always follow the guidance of your healthcare provider regarding the use of this medication
